Living tissue build using man-made 3D print microscopic vascular networks

Category: HealthCare, Science, Technology 6 0

The world is advancing not only in the field of electronics but also in the field of science. The medical sector is considered to be one of the most growing markets. The researchers are always in the hunt for finding out techniques that can help improve the diagnostic methods. The most recent advancement is the development of vascular networks which can help build living tissues in an artificial environment. The vascular network development is a very crucial method as the sustenance of these cells is not as easy as we think.

The researchers have been able to create a living tissue in the lab by mimicking the minutest of the internal structure of the natural tissue. According to the researchers, the supply of oxygen and various nutrients through a capillary network to the living cells that too in an integrated environment is a vital role. The University of California, San Diego researchers have developed a technique of 3D printing microscopic vascular network that helps build a living tissue. They have created a 3D print of the vascular networks similar to the natural network, that is, about 4mm × 5mm long and 600µm thick. The vascular networks can later turn into a channel-like structure using the same cells as that used to build natural blood vessels.

The researchers have named this new method as “μCOB” (microscale continuous optical bioprinting). In this method, a number of different cells are mixed and embedded into a hydrogel. Then the ultraviolet rays and mirrors are used to create a heated-up environment in order to solidify the 3D pattern within the hydrogel. The living cells that are untouched and alive are then able to grow and settle into a new living tissue-like structure. These structures were then implanted into the wounded mice for checking its capability. The results shown by the mice after the bonding of the man-made tissue and the natural mouse tissue leading a healthy living tissue with a continuous blood flow through its own has been astonishing.

Thus, the researcher’s continuous innovation proves that they are leaving no stone unturned.

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